Miami, situated on the Atlantic coast in Southeast Florida, is the world's busiest cruise port. An array of world-famous beaches such as South Beach, which is known for its vibrant nightlife scene, continue to put the city on the map for cruise vacationers. Miami is home to many beautiful and lush national parks and botanical gardens, such as Biscayne National Park and the divine Pinecrest Gardens.

George Town is the capital of the Cayman Islands, one of the most popular cruise-ship destinations in the Caribbean due to its year-round tropical weather. The white-sand beaches and clear blue skies are inviting for visitors looking for a relaxing trip while the tropical rainforests surrounding the town are just waiting to be explored. The laid-back Caribbean vibe, duty-free shopping and inviting waters make George Town a popular choice for divers, families and honeymooners alike.

Cartagena was founded in 1533 and is located on the Caribbean coast in northern Colombia. The walled Old Town boasts some of the most beautiful colonial architecture in South America with cobblestones and colourful facades. It also happens to be one of the safest places in Columbia making it great for cruisers. Make sure not to miss the San Felipe de Barajas Castle and the Palace of the Inquisition.

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The town of Corinto is situated on a northwest Nicaraguan peninsula stretching into the Pacific. Visitors from the mainland will need to cross one of two bridges connected to the peninsula to reach Corinto. While there, the town's lighthouse is a point of interest, dating back to 1876. All goods imported to or exported from the west coast of Nicaragua go through Corinto as the town serves as the country's only Pacific port.

Puerto Quetzal is Guatemala's largest port on the Pacific Ocean. The southern part of Puerto Quetzal is particularly important for both freight and passenger transport. Craft and souvenir markets are situated right at the port. In the immediate vicinity, cruise passengers may also enjoy relaxing bars, a restaurant and performances from Marimba bands. Those who chose to take an inland tour may visit the city of La Antigua.